Alcohol dehydrogenase (ADH) is an enzyme that facilitates the interconversion between alcohols and aldehydes or ketones. This enzyme plays a crucial role in the metabolism of alcohol in the body and can be found across a wide range of organisms, including bacteria, yeast, plants, and animals. It is typically a zinc-containing enzyme that can be found as a dimer or tetramer. The enzyme's active site usually includes a zinc ion, which is essential for its catalytic activity.
Alfa Chemistry provides high-quality alcohol dehydrogenase and related product customization.
Product Detail
| Product Name | Alcohol Dehydrogenase (Crude Enzyme) |
|---|
| Catalog Number | BIOS9031725 |
| CAS Number | 9031-72-5 |
| Enzyme Commission Number | EC 1.1.1.1 |
| Description | Zinc protein. Acts with very broad specificity on primary or secondary alcohols or hemiacetals; however, the enzyme is much less capable of oxidizing methanol than ethanol. |
| Form | Clear to translucent yellow solution |
| Storage | Store at -20 °C or lower, valid for at least 1 month. |
| Notes | Custom production can be done to your specifications. |
Function
The primary function of ADH is to catalyze the oxidation of alcohols to aldehydes or ketones, which can then be further processed in metabolic pathways. The reaction can be summarized as follows:
R-CH2OH + NAD+ → R-CHO + NADH + H+
In this reaction:
- R-CH2OH is the alcohol substrate.
- NAD+ is nicotinamide adenine dinucleotide, which acts as an electron acceptor.
- R-CHO is the resulting aldehyde.
- NADH is the reduced form of NAD⁺.
Applications
Medical and Clinical
- Alcohol Poisoning: ADH activity is a factor in the treatment of alcohol poisoning. Understanding its kinetics can help manage cases of methanol or ethylene glycol poisoning.
- Pharmacology: Some drugs inhibit ADH to prevent the metabolism of toxic alcohols.
Industrial and Biotechnological
- Biocatalysis: ADH enzymes are used in the synthesis of chiral alcohols, important intermediates in pharmaceuticals.
- Biosensors: ADH can be used in biosensors to detect ethanol levels in blood, breath, or beverages.
Choose Alfa Chemistry
Unlock the potential of your research and industrial applications with Alfa Chemistry's high-quality alcohol dehydrogenase. Tailor-made to meet your exact specifications, our customizable products deliver precise results for all your needs. Contact us today to discover how our alcohol dehydrogenase can drive your success and innovation.
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