Mannitol dehydrogenase (MDH) is an enzyme that plays a critical role in the metabolic pathways of various organisms, particularly those that utilize mannitol, a sugar alcohol, as a source of energy or as a storage form of carbohydrate. It is typically a protein composed of several subunits, with a distinct active site where the substrate (mannitol) and the coenzyme (NAD+) bind.
Alfa Chemistry offers high-quality mannitol dehydrogenase that is briefly purified from engineered E. coli.
Product Detail
| Product Name | Mannitol Dehydrogenase (Crude Enzyme) |
|---|
| Catalog Number | BIOS144941297 |
| CAS Number | 144941-29-7 |
| Enzyme Commission Number | EC 1.1.1.255 |
| Source | E. coli |
| Synonyms | MTD; NAD-dependent mannitol dehydrogenase |
| Reaction | D-mannitol + NAD+ = D-mannose + NADH + H+ |
| Appearance | Clear to translucent yellow solution |
| Package | 100 mL |
| Activity | Undetermined |
| Applications | Diagnostics; biotechnology |
| Storage | Store at -20 °C or lower, for at least 1 month. |
| Notes | Custom production can be done to your specifications. |
Biological Significance
- Osmoregulation: In plants, mannitol acts as an osmoprotectant, helping cells to maintain osmotic balance under stress conditions such as drought or high salinity. The enzyme is crucial for the conversion between mannitol and mannose, thus managing cellular osmotic pressure.
- Energy Metabolism: In certain bacteria and fungi, mannitol dehydrogenase is part of the metabolic pathway that breaks down mannitol for energy production, feeding into central metabolic pathways like glycolysis.
- Storage Carbohydrate Metabolism: In some microorganisms and algae, mannitol serves as a storage carbohydrate, and the enzyme helps to mobilize this stored form by converting it back to a usable sugar.
Choose Alfa Chemistry
Choose Alfa Chemistry for top-tier mannitol dehydrogenase and bespoke product customization tailored to your unique requirements. Our premium-quality enzymes are ideal for diverse applications, including biosensors and diagnostic assays. Contact us today to explore our customizable options and discover how we can supply the enzymes you need for your research and development endeavors.
Our products and services are for research use only.
