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NAD<sup>+</sup>
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NAD+

Product Name: NAD+ (β-Nicotinamide Adenine Dinucleotide, Oxidized Coenzyme I)
Catalog Number: BIOS53849
Molecular Formula: C21H27N7O14P2
Appearance: White Powder
CAS Number: 53-84-9
Molecular Weight: 663.43
Purity: ≥ 95%

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Description

β-Nicotinamide adenine dinucleotide (NAD+), also known as oxidized coenzyme I, plays a crucial role in the field of biopharmaceuticals. NAD+ serves as a pivotal electron carrier and coenzyme for numerous dehydrogenases in the human body. It acts as a vital link between the tricarboxylic acid (TCA) cycle and the respiratory chain, facilitating the transfer of hydrogen atoms removed during metabolic processes to flavoproteins. This electron transfer is essential for cellular respiration and energy production, making NAD+ indispensable for maintaining cellular metabolism and overall physiological function.

As a leading innovator in the synthetic biology industry, Alfa Chemistry offers high-quality, eco-friendly NAD+. This versatile compound has broad applications in nutrition and health, biomedicine, cosmetic medicine, daily chemicals, and sustainable agriculture.

Product Detail

Product NameNAD+ (β-Nicotinamide Adenine Dinucleotide, Oxidized Coenzyme I)
Catalog NumberBIOS53849
CAS Number53-84-9
AppearanceWhite Powder
Purity ≥ 95%
Content90%
Sodium Ion (Na+) Content≤ 1%
Moisture Content≤ 5%
pH2 - 4
Endotoxin ≤ 0.2 EU/mg
Lead (Pb)≤ 0.1 ppm
Arsenic (As)≤ 0.1 ppm
Mercury (Hg)≤ 0.1 ppm
Cadmium (Cd)≤ 0.1 ppm

Functions

NAD+ serves several critical roles in cellular metabolism:

  • Redox Reactions: NAD+ functions as an oxidizing agent in redox reactions, accepting electrons and becoming reduced to NADH. It is an essential part of many enzymatic reactions, including those in:
    • Glycolysis: The first step of glucose metabolism.
    • Citric Acid Cycle (Krebs Cycle): A key metabolic pathway that completes the oxidation of organic molecules.
    • Electron Transport Chain: Where NADH is oxidized back to NAD+, releasing energy used to produce ATP, the primary energy currency in the cell.
  • Coenzyme Activity: NAD+ works with dehydrogenases, a group of enzymes that catalyze the removal of hydrogen atoms from substrates, facilitating their oxidation.
  • Signal Transduction: NAD+ is a precursor to cyclic ADP-ribose and nicotinamide mononucleotide, which are involved in calcium signaling and other cellular processes.
  • DNA Repair: NAD+ is involved in the post-translational modifications of proteins, including poly-ADP-ribosylation, a process that is important in DNA repair mechanisms.
  • Gene Expression: Sirtuins, a family of NAD+-dependent deacetylases, are involved in the regulation of transcription, apoptosis, and aging processes.

Choose Alfa Chemistry

Alfa Chemistry is a trusted provider of high-quality NAD+, catering to a wide array of applications. Our NAD+ is designed to meet rigorous standards, ensuring reliability and eco-friendliness, making it ideal for your research and development needs. By choosing Alfa Chemistry, you can be confident in receiving a top-notch NAD+ product. For more information or to place an order, please contact us today.

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