Biosynthesis / Alfa Chemistry
Nisin
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Nisin

Nisin, a polypeptide substance produced by Lactococcus lactis, is rapidly hydrolyzed into amino acids under the physiological pH conditions of the human body and by the action of α-chymotrypsin upon consumption. Unlike other antibiotics, it does not alter the normal intestinal flora or cause resistance issues, and it does not have cross-resistance with other antibiotics. Nisin is a highly efficient, non-toxic, safe, and excellent natural food preservative. It effectively inhibits and kills the vegetative cells and spores of various Gram-positive bacteria, such as Bacillus stearothermophilus, Bacillus cereus, Staphylococcus aureus, Listeria monocytogenes, and Clostridium botulinum. When added to food, nisin significantly reduces sterilization temperature and time, preserving the original nutritional content, flavor, and color of the food, while saving considerable energy. It is widely used in the preservation of meat products, dairy products, vegetable protein foods, canned foods, fruit juice drinks, and heat-treated sealed packaged foods. Nisin also finds applications in cosmetics and health care products.

Alfa Chemistry offers high-quality nisin extracted from Lactococcus lactis fermentation products through modern biotechnology.

Product Detail

Product NameNisin
CatalogBIOS1414455
CAS No.1414-45-5
Molecular FormulaC143H230N42O37S7
Molecular Weight3354.07
Appearance Light brown to milky white powder
Potency≥ 900 IU/mg
Loss on Drying≤ 3%
Pb≤ 1 mg/kg
Total Aerobic Microbial Count≤ 10 CFU/g
Salmonella in 25gNegative

Main features

  • Effectively inhibits the growth and reproduction of numerous Gram-positive bacteria responsible for food spoilage, particularly heat-resistant Bacillus and Clostridium botulinum. It also has a strong inhibitory effect on the spores they produce.
  • Lowers the sterilization temperature required for food processing, shortens the sterilization time, enhances food quality, minimizes nutritional loss, and extends storage duration.
  • Offers high cost efficiency with minimal usage.
  • Once ingested, it is broken down into various amino acids by the body's proteases, leaving no residue, causing no drug resistance, and having no adverse effect on beneficial human probiotics.

Choose Alfa Chemistry

Unleash the potential of nisin with Alfa Chemistry! Our top-quality nisin is manufactured through cutting-edge fermentation techniques using Lactococcus lactis, ensuring unparalleled purity and effectiveness. Opt for Alfa Chemistry for premium nisin that delivers exceptional performance even at low doses, making it a highly cost-effective solution. Contact us today to make a smart choice for your needs.

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