Nitrile hydratase (NHase, EC 4.2.1.84) is an enzyme that catalyzes the hydration of nitriles to their corresponding amides. This biocatalytic process is significant in both industrial applications and biochemical research due to its high specificity and efficiency.
Alfa Chemistry offers high-quality nitrile hydratase, which is briefly purified from engineered E. coli, ensuring a reliable and efficient enzyme for research purposes.
Product Detail
| Product Name | Nitrile Hydratase (Crude Enzyme) |
|---|
| Catalog Number | BIOS82391375 |
| CAS Number | 82391-37-5 |
| Enzyme Commission Number | EC 4.2.1.84 |
| Source | E. Coli |
| Appearance | Clear to translucent yellow solution |
| Enzyme Activity | Undetermined |
| Package | 100 mL |
| Enzymatic Reaction | an aliphatic amide = a nitrile + H2O |
| Synonyms | 3-cyanopyridine hydratase; NHase; L-NHase; H-NHase; acrylonitrile hydratase; aliphatic nitrile hydratase; nitrile hydro-lyase |
| Systematic Name | Aliphatic-amide hydro-lyase (nitrile-forming) |
| Cofactor(s) | Pyrroloquinoline quinone |
| Application | Synthesis; degradation; environmental protection |
| Storage | Store at -20 °C or lower, for at least 1 month |
Applications in Biocatalysis and Green Chemistry
- Acrylamide Production: NHase is employed industrially for the production of acrylamide, a monomer used in polymer synthesis. The process is environmentally friendly compared to traditional chemical methods.
- Pharmaceuticals: It aids in the synthesis of intermediates for pharmaceuticals. For example, the conversion of nicotinonitrile to nicotinamide, an essential vitamin component.
- Agrochemicals: NHase can synthesize precursors to herbicides and pesticides, offering a cleaner production method.
- Bioremediation: NHase-expressing microbes can be employed to detoxify environments contaminated with nitrile pollutants, converting toxic nitriles to less harmful amides.
- Waste Valorization: NHase can be used to transform industrial waste nitriles into valuable chemical products, thus contributing to waste reduction and resource efficiency.
Choose Alfa Chemistry
Alfa Chemistry is dedicated to offering an extensive array of biological enzymes, underpinned by extensive research and production expertise in biochemistry. With a robust foundation in the industry, Alfa Chemistry is always prepared to deliver high-quality products and professional technical support to meet your requirements. For more information about our nitrile hydratase products, please contact us.
Our products and services are for research use only.
