Enzymes are proteins that act as biological catalysts by accelerating chemical reactions. Most industrial enzymes are hydrolytic in nature (hydrolases), catalyzing breakdown of natural polymeric substrates like proteins, starches, lipids, fibers, and complex cell walls, into simpler molecules. The most frequently used enzymes fall in the broad categories of proteases, amylases, and cellulases. Additional activities include pectinase, xylanase, phytase, lipase, lactase, invertase, isomerase, oxidase, and catalase categories. Enzymes play an amazingly vital role in business and are essential to the assembly of a lot of industrial products. Therefore, the research and optimization of enzymes are particularly important.
How Can We Help You?
As a professional provider of enzyme services, Alfa Chemistry provides services from computational design to novel enzyme discovery to commercial scale-up. Whether you're looking for new enzymes, looking to improve your enzyme's function, or aiming to lower the costs, we can provide you with the best services in your enzyme development or production. Services we can provide including but not limited to the followings:
New enzymes discovery
Optimization of enzyme function and stability
Fermentation process development
Scale-up manufacturing and process development
New enzymes discovery
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Discovery of new enzymes refers to the identification of entirely new types of biocatalysts, the discovery of new functions in families with previously characterized members, and the discovery of enzymes with different substrate specificities or preferred reaction conditions including temperature, pH, salinity, or solvent preferences.
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Common methods of enzyme discovery include shotgun metagenomic sequencing, activity-guided screening, and PCR-based screening.
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We use a combination of bioinformatics and 3D molecular modeling to identify your best target enzymes in the shortest possible time.
Optimization of enzyme function and stability
- Enzymes work by lowering the activation energy of chemical reactions, and the activity and stability of enzymes play an important role in the efficiency of these reactions.
- Many factors must be considered during the optimization of an enzyme assay, such as the choice of buffer and its composition, the type of enzyme and its concentration, as well as the type of substrate and concentrations, the reaction conditions, and the appropriate assay technology.
- We use a broad and constantly expanding toolkit of evolutionary, computational, and rational protein engineering approaches to iteratively improve catalytic activity, enzyme stability, specificity, and expression.
Fermentation process development
- Many fermentation procedures require enzymes to speed up the process.
- Alfa Chemistry can provide design of experiments at lab scale to quickly develop fermentation processes, with a proven record of transferring to commercial scale.
Scale-up manufacturing and process development
- We can perform pilot scale fermentation in one of our facilities with capacities up to 3,000L.
- We can optimize the production and purification processes.
Why Choose Alfa Chemistry?
As a leading enzyme services provider, Alfa Chemistry works towards pre-defined goals, and prides itself on being tied to your success. We work as an extension of your team to help you to adopt the right principles, improve product quality and enhance overall project delivery.
Alfa Chemistry specializes in providing professional enzyme services to help our customers accelerate their own R&D, optimize production, reduce the costs, and we are always available to answer any questions you may have during the R&D and production process. Please do not hesitate to contact us if you are in need of assistance.
Our products and services are for research use only.
