Natamycin, also known as pimaricin, is a naturally occurring antifungal agent produced by the bacterium Streptomyces natalensis and related species. This polyene macrolide features a large lactone ring and multiple conjugated double bonds, which enable it to bind specifically to ergosterol, an essential component of fungal cell membranes. By binding to ergosterol, natamycin disrupts the membrane's structure and function, increasing its permeability and causing leakage of cellular contents, ultimately leading to cell death. Unlike some other antifungal agents, natamycin has minimal impact on cholesterol, making it less toxic to human cells. For decades, natamycin has been widely used in various applications, including food preservation and medical treatments, to prevent fungal growth.
Alfa Chemistry offers high-quality natamycin that is extracted from Streptomyces natalensis fermentation products using modern biotechnology.
Product Detail
| Product Name | Natamycin |
|---|
| Catalog | BIOS7681938 |
| CAS No. | 7681-93-8 |
| Molecular Formula | C33H47NO13 |
| Molecular Weight | 665.73 |
| Synonym(s) | Pimaricin; tennecetin |
| Appearance | Off‐white to cream‐colored powder |
| Odor | No smell |
| Purity (on dry basis) | ≥ 95% |
| Loss on Drying | ≤ 8% |
| Residue after burning | ≤ 0.5% |
| Lead (Pb) | ≤ 1 mg/kg |
| Arsenic (As) | ≤ 1 mg/kg |
| Total Aerobic Microbial Count | ≤ 100 CFU/g |
Applications
Food Preservation
- Dairy Products: Natamycin is commonly used to prevent the growth of molds and yeasts on cheese and other dairy products. It is often applied as a surface treatment.
- Meat and Sausages: It is also used to extend the shelf life of processed meats and sausages by inhibiting fungal growth.
- Baked Goods: Natamycin can be used to prevent mold spoilage in baked goods.
Medical Uses
- Ophthalmic Treatments: Natamycin is used to treat fungal infections of the eye. It is available in the form of eye drops.
- Topical Antifungal: It can be used in topical creams and ointments to treat skin infections caused by fungi.
Agriculture Uses
- Fungicide: Natamycin is sometimes used as a fungicide to protect crops from fungal infections.
Advantages
- Broad-Spectrum Activity: Effective against a wide range of fungi, including molds and yeasts.
- Low Resistance Development: Fungi are less likely to develop resistance to Natamycin compared to some other antifungal agents.
- Safety: Due to its low toxicity and minimal absorption, Natamycin is considered safe for human consumption and use in medical applications.
Choose Alfa Chemistry
Alfa Chemistry offers high-quality bio-based natamycin products. Our natamycin is extracted from Streptomyces natalensis fermentation products using modern biotechnology to ensure its purity and effectiveness. Whether you want to preserve food, treat fungal infections or protect crops, our natamycin can help you achieve your goals. Contact us today to make a smart choice for your needs.
Our products and services are for research use only.
